The Irish Kidney Research Project (IKGP) works closely with many groups in Ireland and abroad. The IKGP in based at Beaumont Hospital and the Royal College of Surgeons in Ireland - RCSI (Dublin). Key collaborations include:
Royal College of Surgeons in Ireland
Profile - Royal College of Surgeons (rcsi.com)
Prof. Gianpiero Cavalleri's lab has been the centre of most of IKGP's work in Ireland. His lab has had MD, PhD, and post-doc scholars working on the inherited kidney diseases.
Katie has created an efficient pipeline for the gene sequencing of patients with inherited kidney disease. She is particularly interested in modifier genes and the role they play in disease phenotype.
Ed is a post doc in Prof Cavalleris lab and has played a critical role in designing studies to look at impact of polygenic factors in outcome of monogenic and polygenic kidney disease.
Omri is a post Doc working in Prof Cavalleris lab specialising as a bioinformatician and data scientist. Omri has contributed to the interpretation of whole exome sequences coming from inherited kidney disease clinic and in particular is studying impact of rare variation ion influencing phenotype.
Sahin is a data scientist and has played a major role in interpretation of whole exome sequences coming from inherited kidney disease clinic
Pathology Department, Beaumont Hospital
Brendan and Neil have played a critical role in the IKGP in reviewing renal pathology of cases with rare inherited kidney disease.
University College Dublin
John Crean Profile | University College Dublin (ucd.ie)
Recently we have developed a collaboration with Dr John Crean at UCD to study the impact of additional gene variants on phenotype of kidney disease. John has developed technology to create “ORGANOIDS “ which are mini kidneys in a test tube. These organoids can be studies to better understand the impact of gene variations on kidney disease
Catherine Godson Profile | University College Dublin (ucd.ie)
Catherine has collaborated with IKGB for many years having established the North Dublin Renal Biobank.
Trinity College Dublin
Mark Little : Trinity Research - Trinity College Dublin (tcd.ie)
Mark was a founding member of rare Kidney Disease biobank with whom the IKGP has had a long standing collaboration
The Irish Kidney Gene Project has established collaborations with numerous centres of excellence in renal genetics in order to advance knowledge of kidney renal genetics more rapidly. At each of these centres with expertise in specific types of inherited kidney disease, we share samples and anonymous clinical information in order to accelerate the discovery of new kidney disease mechanisms.
These collaborators include:
ERKnet- European Reference Network for Rare Kidney Disease. The Irish Kidney gene Project has collaborated with multiple members of ERKnet a European consortium to study rare inherited kidney disease.We have presented findings on our work on rare kidney disease at their annual meeting
ERKNet: The European Rare Kidney Disease Reference Network: ERKNet.
Dr Rasheed Gbadegesin -Duke University Medical Centre, North Carolina, United States. Active collaboration with Rasheed we have studied different forms of inherited focal segmental glomerulosclerosis.
Rasheed Adebayo Gbadegesin | Duke Molecular Physiology Institute | Duke Molecular Physiology Institute
Dr Anthony Bleyer – Wake Forest University, School of Medicine, North Carolina, United States. Tony Bleyer has directed a research program on autosomal dominant interstitial kidney disease. His team has contributed to the identification of numerous genes linked to inherited kidney disease. Tony coordinates a diagnostic laboratory with the Broad Lab at Harvard for the diagnosis of MUC1 Nephropathy, of which there are numerous cases in Ireland.
Anthony J. Bleyer, MD, MS | Wake Forest University School of Medicine (wakehealth.edu)
Dr Stan Kmoch and Dr. Martina Živna. Stan Kmoch and Martina Zivna are leaders in the field of research pertaining to autosomal dominant interstitial kidney disease (ADTKD). They have assisted us in the discovery of new genes associated discovered new genes associated with the development of autosomal dominant familial interstitial nephritis with their help.
Prof. Ing. Stanislav Kmoch, CSc. | Biocev
Mgr. Martina Živná, Ph.D. | Charles University (cuni.cz)
Dr Peter Harris - Mayo Clinic, Rochester, Minnesota. Peter has been at the centre of autosomal dominant polycystic kidney disease research for over three decades. The majority of the genes associated with ADPKD, including PKD 1 and PKD2, were discovered with the assistance of his team. His laboratory has graciously hosted our scientists for periods of intensive training in ADPKD data.
Overview - Polycystic Kidney Disease Discovery Laboratory - Mayo Clinic Research
Dr Irene Capelli - Bologne Italy. Dr. Capelli is Nephrologist in Bologna - Italy . We investigate Adult Polycystic Kidney Disease jointly. We have hosted several of her junior staff members in Dublin for research periods.
Irene Capelli — University of Bologna — Home Page (unibo.it)
Dr Friedhelm Hildrbrandt. Friedhelm is chief of nephrology at Boston Childrens Hospital. He has been generous with his time and has hosted Dr Dervla Connaughton in his lab contributing to the interpretation of more than 150 whole exome sequences from IKGP patient .
Friedhelm Hildebrandt | Harvard Catalyst Profiles | Harvard Catalyst
Prof Jan Halbritter - University of Berlin. For many years we have had a collaboration with Jan particularly studying factors associated phenotype of Polycystic Kidney Disease and gene interactions impacting the phenotype of Polycystic Kidney Disease. We have also recently started to work with Jan regarding Familial Interstitial Kidney Disease and autosomal dominant tubulointerstitial kidney disease (ADTKD).
Prof. Dr. med. Jan Halbritter: Medizinische Klinik mit Schwerpunkt Nephrologie und Internistische Intensivmedizin - Charité – Universitätsmedizin Berlin (charite.de)
Dr John Sayer MD PhD. John Sayers has collaborated with Irish kidney gene project studying both interstitial kidney disease and adult polycystic kidney disease.
Staff Profile | Faculty of Medical Sciences | Newcastle University (ncl.ac.uk)
Prof Graham Lord - University of Manchester. Graham Lord has collaborated with the Irish Kidney Gene Project for more than 10 years. Graham established the UKIRTC data set more than 10 years ago and has been the data set that we have utilised to study GWAS factors associated with transplant outcome and risk factors associated with donor cause of death and age of ESRD.
https://www.bmh.manchester.ac.uk/about/people/leadership/graham-lord/
Was this page useful?